In the development of allergen-specific IgE detection reagents, the quality of the core raw material, anti-human IgE antibody, directly determines the performance of the reagent. Detection of specific IgE levels in serum is the “gold standard” for the in vitro diagnosis of allergic diseases. IgE, like other immunoglobulins (such as IgG, IgA, and IgM), is composed of heavy and light chains. Its class is uniquely determined by the constant region of the heavy chain: IgE has the ε chain, IgG has the γ chain, IgA has the α chain, and IgM has the μ chain.Many common anti-human IgE antibodies, due to targeting common epitopes or light chains, are prone to cross-react with other immunoglobulins, affecting specificity. In contrast, KPL anti-human IgE (ε chain) antibody precisely targets the unique ε heavy chain constant region of the IgE molecule, ensuring that the antibody has extremely high specificity, very low background signal, and excellent detection accuracy, providing a reliable guarantee for the development of high-performance reagents.

The KPL anti-human IgE (ε chain) antibody, with its high specificity and versatility, has become a core tool in the field of allergy detection. It can precisely recognize the Fc segment (ε chain) shared by human IgE molecules, unaffected by the type of allergen (such as dust mites, pollen, or food allergens), enabling unified detection of various specific IgEs. It can be efficiently adapted to both single-item and mixed allergen detection systems.Moreover, due to its extremely high sensitivity and specificity, the KPL anti-human IgE (ε chain) antibody can stably bind to IgE, effectively avoiding cross-reactions with other immunoglobulins such as IgG and IgA. This ensures the accuracy and reliability of the detection results.Currently, this antibody has been widely used in specific allergen detection, in vitro diagnosis, and research of IgE-related diseases.

Diagnostic technology platforms applicable for the KPL anti-human IgE (ε chain) antibody:

? ELISA/Chemiluminescence: As the core detection antibody, it constructs a highly sensitive sandwich assay detection system.

? Lateral flow immunoassay: As a labeled antibody, it aids in the development of rapid POCT products.

? Western blotting: Used to confirm IgE responses elicited by specific proteins.

? Flow cytometry: Used to analyze IgE expression on the surface of B cells.

Advantages of the KPL anti-human IgE (ε chain) antibody product:

? High specificity: Precisely targets the Fc segment (ε chain) of human IgE, with no cross-reactivity with other immunoglobulins such as IgG and IgA.

? Strong versatility: Suitable for different types of allergens and can be adapted to both single-item and mixed allergen detection systems

? Platform compatibility: Applicable to various immunoassay technology platforms, including ELISA, chemiluminescence, and Western blotting.

? Multiple labeling options: Available in unlabeled, enzyme-labeled, biotin-labeled, and fluorescent-labeled forms.

The KPL range of anti-human IgE secondary antibodies, with their outstanding performance and diverse options, has become the preferred product for immunological research and the development of allergen diagnostic reagents. Based on the core design targeting the ε chain of IgE, KPL provides reliable solutions for chemiluminescence, ELISA, Western blotting, and rapid detection platforms, facilitating the smooth progress of scientific research and diagnostic work.

KPL (Kinetic Plasmonics Laboratories) is a company with a profound history and outstanding reputation in the field of biosciences. As one of the world's early biotechnology companies to commercialize affinity-purified secondary antibodies, KPL has laid a solid foundation for its development through its pioneering position in this area. In addition, KPL is also one of the world's largest producers of secondary antibodies and substrate chromogenic systems, with nearly 40 years of product development experience, and has accumulated extensive professional knowledge and technical strength. The company is certified under the ISO 13485 quality system, ensuring that all products have minimal batch-to-batch variation and reliable quality. KPL's products are characterized by high purity, high sensitivity, and a high signal-to-noise ratio (strong signal, low background), and are trusted by researchers and diagnostic companies. In 2013, KPL was acquired by SeraCare, a supplier of in vitro diagnostic reagents, further consolidating its leading position in the industry. Established in 1984, SeraCare is a major partner for global in vitro diagnostic manufacturers and clinical laboratories, and became part of the LGC Group in 2018.

Beijing XMJ Scientific Co., Ltd, as the exclusive distributor of LGC·Seracare·KPL brands in China, is committed to promoting KPL's excellent products in China and providing high-quality products and professional services to the broad scientific research community in the country.If you are interested in our products, please feel free to call XMJ's national customer service hotline at 400-050-4006 or visit our official website at m.aoxiangbz.com for more information.